Cell Culture Media, Supplements, and Reagents
Selleck Chemical LLC Evacetrapib (LY2484595) S2925-5mg
Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5 5 nM elevates HDL cholesterol without increases in aldosterone or blood pressure Phase 3
Apexbio Technology LLC Chlortetracycline HCl 64-72-2 250mg
Chlortetracycline HCl (64-72-2) is a small-molecule inhibitor targeting the bacterial 30S ribosomal subunit It is designed to inhibit protein synthesis by interfering with aminoacyl-tRNA binding and preventing elongation of the polypeptide chain Chlortetracycline HCl exerts its biological activity primarily through reversible binding to the bacterial 30S ribosomal subunit resulting in inhibition of bacterial protein synthesis Based on these pharmacological properties Chlortetracycline HCl holds research potential in controlling bacterial contamination in cell culture systems studying bacterial resistance mechanisms evaluating antibiotic susceptibility and investigating microbial protein biosynthesis pathways in vitro
Apexbio Technology LLC (-)-Tetramisole 16595-80-5 5g
(-)-Tetramisole is an immunomodulatory agent that stimulates nicotinic acetylcholine receptors leading to the activation of T-lymphocytes macrophages and phagocytic cells to enhance cell-mediated immune responses (-)-Tetramisole exerts its biological activity primarily through activation of nicotinic acetylcholine receptors Additionally it is utilized in the investigation of epigenetic regulation pathways involving lysine-specific demethylase 1 (LSD1) serving as a research tool to study chromatin modulation mechanisms and gene expression control Based on these pharmacological properties (-)-Tetramisole holds research potential in immunological signaling studies and tumor biology
Biotium CD11b MAC-1 Microglial Marker ITGAM271 CF647 conjugate 0.1mgmL
CD11b MAC-1 Microglial Marker ITGAM271 CF647 conjugate 0.1mgmL
Apexbio Technology LLC Irsogladine 57381-26-7 50mg
Irsogladine (CAS 57381-26-7) is a small molecule inhibitor of phosphodiesterase 4 (PDE4) and exhibits binding affinity for muscarinic acetylcholine receptors In preclinical studies irsogladine administration at 300 and 500 mg/kg/day produced a dose-dependent suppression of angiogenesis in wild-type mice reducing neovascularization by 21% and 45 3% respectively with statistical significance (P 0 02 P 0 001) These properties support its utility in investigating the modulation of cyclic AMP signaling cholinergic pathways and angiogenesis in biomedical research contexts
Medchemexpress LLC Potassium oxonate | 2207-75-2 | 99.9% | 195.17 | 500 MG
Potassium oxonate (Potassium azaorotate) is a uricase inhibitor primarily used in research to inhibit the phosphorylation of 5-FU and for creating hyperuricemia animal models. This selective competitive inhibitor blocks hepatic uricase and is metabolized in the gastrointestinal tract, distributing primarily in small intestine cells where it is converted to cyanuric acid.
- Inhibits the phosphorylation of 5-FU to 5-fluorouridine-5'-monophosphate.
- Utilized in animal modeling to create hyperuricemia models.
- Functions as a selective competitive uricase inhibitor.
- Blocks the action of hepatic uricase.
- After metabolism, primarily distributes within the cells of the small intestine.
- Converted to cyanuric acid in the gastrointestinal tract through two pathways.
eMolecules Medchem Express / Natamycin / 50mg / 446272095 / HY-B0133 / / 7681-93-8 / MFCD00135085 / 665.733 / C33H47NO13
Medchem Express / Natamycin / 50mg / 446272095 / HY-B0133 / / 7681-93-8 / MFCD00135085 / 665.733 / C33H47NO13
![Medchemexpress LLC 4-[[6-(cyclohexylmethoxy)-7H-purin-2-yl]amino]-N,N-diethylbenzamide | 444723-13-1 | MFCD09264153 | 99.1% | 422.52 g/mol | C23H30N6O2 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000239705.png-250.jpg)
Medchemexpress LLC 4-[[6-(cyclohexylmethoxy)-7H-purin-2-yl]amino]-N,N-diethylbenzamide | 444723-13-1 | MFCD09264153 | 99.1% | 422.52 g/mol | C23H30N6O2 | 10 MG
NU6140 is a small-molecule research inhibitor described as a selective CDK2-cyclin A inhibitor that also inhibits Aurora A and Aurora B kinases. Supplied as a solid with reported high purity, it is used for cell-cycle and kinase research in both in vitro and in vivo experiments.
- Selective CDK2-cyclin A inhibitor (IC50 0.41 μM).
- Also inhibits Aurora A and Aurora B (IC50 67 nM and 35 nM).
- High reported purity suitable for biochemical and cellular assays.
- High DMSO solubility enables concentrated stock solutions.
- Stable when stored as powder or in recommended solvent conditions.
- Offered in small milligram pack sizes for early-stage research.
Apexbio Technology LLC Etifoxine hydrochloride 56776-32-0 10mg
Etifoxine hydrochloride (CAS 56776-32-0) is a small molecule that modulates GABAA receptor activity with selectivity towards receptors containing 2 or 3 subunits In neuronal cell culture models it enhances GABAA receptor-mediated responses Etifoxine also binds to the translocator protein (TSPO) a mitochondrial protein involved in neurosteroidogenesis In preclinical and clinical studies etifoxine demonstrates anxiolytic effects without producing sedative muscle relaxant or cognitive impairment typically associated with benzodiazepines Additionally it has been reported to promote axonal regeneration supporting its utility in neuropharmacological and neuroregeneration research
Selleck Chemical LLC Anisomycin
Anisomycin (Flagecidin Wuningmeisu C) is a bacterial antibiotic isolated from Streptomyces griseolus which inhibits protein synthesis and also act as a JNK activator Anisomycin upregulates autophagy and increases apoptosis
Pfanstiehl Inc Streptozotocin (S-141) 5g - API, active pharmaceutical ingredient CAS: 18883-66-4
Streptozotocin(S-141) 5g - API, active pharmaceutical ingredient CAS: 18883-66-4
